“Use it and lose it” is often said when it comes to antibiotic resistance concerns. Every time we use an antibiotic (in a person or animal), there’s some potential for resistance to emerge. The more we use antibiotics, and the worse we use them, the greater the risk, generally speaking.

Questions about the (rampant) use

Bacteria are smarter than we give them credit for.
Or maybe we’re not a bright as we think we are.

Antimicrobial stewardship is sometimes (wrongly) assumed to simply be the practice of “using fewer antimicrobials,” but it’s more complex than that, because the issue is complex. At face value, overall reduction in antimicrobial use is

The post below is reproduced from CANresist.blog. It applies equally for veterinary medicine.

I think most people buy into the concept of fossil fuels being finite resources. Someday, they’ll run out or logistics and cost of extraction will make them impractical. Accordingly, we’re thinking about ways to reduce and improve use (to delay the

Aug 8, 2018 addendum: updated versions of the CARSS report are available here:

English: https://www.canada.ca/content/dam/phac-aspc/documents/services/publications/drugs-health-products/canadian-antimicrobial-resistance-surveillance-system-2017-report-executive-summary/CARSS-Report-2017-En.pdf

French: https://www.canada.ca/content/dam/phac-aspc/documents/services/publications/drugs-health-products/canadian-antimicrobial-resistance-surveillance-system-2017-report-executive-summary/SCSRA-Rapport-2017-Fr.pdf

The 2017 Canadian Antimicrobial Resistance Surveillance System (CARSS) report was just released, and as always it contains a lot of data (up to and including 2016). Some are interesting, some are concerning, some are encouraging.

I’m not going

The World Health Organization has released new guidelines on the use of “medically important antimicrobials” (MIAs) in food animals. Here’s a list of their recommendations, along with the strength of each recommendation and quality of evidence behind it.

  1. We recommend an overall reduction in use of all classes of medically important antimicrobials in food-producing

It’s commonly been stated that it’s important to finish your course of antibiotics (whether “your” refers to a person or animal), as a means of reducing the risk of developing antibiotic resistance. That’s never made much sense to me, since more antibiotic exposure is more likely to lead to a risk of resistance emerging. However,

DNA helix2I’ve had a lot of emails over the past few months from colleagues from other countries, asking if we’re finding much mcr-1 in Canada. mcr-1 is a gene that makes bacteria resistant to colistin, a “drug of last resort” in people with some highly resistant infections.  The gene has emerged in bacteria from both animals