Worms & Germs Blog

Tag Archives: antibiotics

More bad news on the MRSP front

Posted in Dogs
Well, "news" perhaps isn’t the best description since we’ve been seeing it for a while, but a paper in an upcoming edition of the Journal of Clinical Microbiology (Gold et al. 2014) entitled "Amikacin resistance in Staphylococcus pseudintermedius isolated from dogs" provides published support for the trend we’ve been seeing. Staphylococcus pseudintermedius is an important… Continue Reading

Cry me a river…crackdown on Angels’ Eyes

Posted in Dogs
Finally. While having nothing to do with my previous rants on the topic, the FDA has issued warning letters to the manufacturers of Angels’ Eyes and similar products that are vaguely disguised antibiotics sold for purely cosmetic reasons, and without a veterinary prescription. These products have been widely available to decrease tear staining (hardly a… Continue Reading

FDA releases 2011 antimicrobial resistance data

Posted in Other animals
The US Food and Drug Administration has released the 2011 NARMS (National Antimicrobial Resistances Monitoring System) executive report. It’s a good-news/bad-news outcome, which may be as good as can be expected, but at least there’s some good news. Here are some areas that were highlighted by the FDA. Eighty-five percent of non-typhoidal Salmonella collected from humans… Continue Reading

Guidelines for the diagnosis and treatment of pyoderma in dogs

Posted in Dogs
Clinical guidelines are fairly new (and limited) in veterinary medicine, although they’re widespread in human medicine. Following up on recent guidelines for diagnosis of treatment of urinary tract infections in dogs and cats, a working group from the International Society for Companion Animal Infectious Diseases (ISCAID) has completed guidelines for the treatment of a common… Continue Reading

“Angels’ eyes”…and this is a good idea because…?

Posted in Cats
Antibiotic resistance is a big deal. Lots of people and animals die because of it every year. It costs the healthcare systems (human and veterinary) tremendous amounts of money and it’s not getting better. It’s been clear for years that we have to do a better job of using antibiotics responsibly, in both animals and… Continue Reading

The “criticall important antibiotic” debate

Posted in Other diseases
Last week, I mentioned the antibiotic use plenary session at the ASM-ESCMID conference on methicillin-resistant staphylococci in animals. The session was designed to discuss the use of "critically important antibiotics" in companion animals – drugs like carbapenems (imipenem, meropenem) and vancomycin, which are used for treating serious multidrug-resistant infections in people as well. After the… Continue Reading

The big gun antibiotic controversy

Posted in Dogs
I’m getting ready for next week’s ASM/ESCMID conference on methicillin-resistant staphylococci in animals, for which I’m involved in a plenary session about critically important antibiotics in companion animals. The whole area of antibiotics and animals in complex and controversial (and made worse by political agendas, lack of evidence and confusion about different issues). Anyway, one… Continue Reading

Human health impact of antibiotic use in animals

Posted in Other animals
Antibiotic use in animals, and the impact on humans is a controversial area. At a conference a few years ago, one of the organizers posed the question, "What percentage of resistance in human pathogens is attributable to antibiotic use in animals?" They had people write their answers on cards, and later in the day they… Continue Reading

Antimicrobial stewardship: Time for change

Posted in Horses
A call to arms from guest blogger and University of Guelph professor, Dr. John Prescott: Watching the global emergence and spread of multi-drug resistant bacteria is like seeing a train wreck in slow motion. There’s a sense of both inexorability and powerlessness. In the March 2013 issue of the Equine Veterinary Journal, Mark Bowen of… Continue Reading

Essential oils…the overlooked MRSA “solution”?

Posted in MRSA/MRSP
Methicillin-resistant Staphylococcus aureus (MRSA) and other antibiotic-resistant bacteria are big problems. They account for millions of illnesses, thousands of deaths and billions of dollars in costs every year internationally. Antibiotic-resistance is a complex issue, but some people try to over-simplify (and under-analyse) the problem. A recent article on Examiner.com is an example. Entitled "MRSA cases… Continue Reading

Horse shipping infections…are drugs the answer?

Posted in Horses
Sometimes, I get a little concerned when research papers get picked up by the press. It’s not necessarily because the research is weak, it’s just that results sometimes get overstated or misinterpreted when they work their way outside of scientific forums. A paper published in the latest edition of the American Journal of Veterinary Research is… Continue Reading

Antibiotics…time to close some loopholes

Posted in Miscellaneous
At a time when there’s much concern about antibiotic use and resistance, and when there’s talk about restricting antibiotic use in animals, it amazes me that some huge, illogical and easy-to-correct loopholes remain in the current system. The approach to access to antibiotics for animals varies greatly in different countries: In some, access to antibiotics… Continue Reading

More on MRSA and meat

Posted in MRSA/MRSP
While it shouldn’t come as a surprise considering other studies, a recent study in PLoS One (O’Brien et al 2012) has caused a bit of a stir in the US. This study, headed up by Dr. Tara Smith’s research group in Iowa, looked for methicillin-resistant Staphylococcus aureus (MRSA) in retail pork. They bought pork from… Continue Reading

Study Seeking “Superbugs” In Horses

Posted in equIDblog
A two-part study (Maddox et al. 2011) was recently published online in the Equine Veterinary Journal looking at antimicrobial resistant "superbugs" in horses in the UK.  The first part of the study had the simple objective of estimating the prevalence of both MRSA nasal colonization and fecal shedding of antimicrobial resistant E. coli in the… Continue Reading

Urinary tract infection treatments guidelines: Dogs and cats

Posted in Cats
Urinary tract disease is a common reason for use (and misuse) of antibiotics. In veterinary medicine, one thing that we lack is clear clinical guidelines (particularly regarding antimicrobial use) to help manage specific types of diseases. In human medicine, there are some excellent guidelines of this kind (e.g. the Infectious Disease Society of America guidelines)… Continue Reading

Swedish antimicrobial guidelines

Posted in Cats
The Swedish Veterinary Association has released an English version of their 2009 "Guidelines for the clinical use of antibiotics in the treatment of dogs and cats". It’s a very comprehensive document that goes through various medical conditions and discusses antibiotic use recommendations. As concerns about antibiotic use and misuse increase, more organizations are putting the… Continue Reading

Skin infections in dogs: Stopping the downward spiral

Posted in Dogs
A large percentage of advice calls that I get about methicillin-resistant staph infections in dogs are regarding skin infections. Skin infections (pyoderma) are a common problem, a leading cause of antibiotic use in dogs, and an often frustrating problem for vets and pet owners alike. One problem is that, unlike many other types of infections, skin… Continue Reading

Drug discovery disparity

Posted in Other diseases
On the way home from an MRSA symposium in the US the other day, I was (perhaps fittingly) listening to a podcast about new antibiotic development. The podcast, by The Lancet Infectious Diseases, discussed the small number of new antibiotics that are in the pipeline (about 15), particularly in contrast to the number of new anti-cancer drugs (about… Continue Reading

Big gun antibiotics in pets

Posted in MRSA/MRSP
Antibiotic resistant bacteria are a huge problem in human medicine, and they’re an increasing problem in veterinary medicine. In pets, we are seeing dramatic increases in multidrug-resistant bacteria, some as a result of transmission from humans and some that are developing in animals. Regardless of the source, infections caused by resistant bacteria are a major… Continue Reading

Musings about antibiotic therapy in dogs and cats

Posted in Cats
I recently attended a meeting to develop antibiotic use guidelines for dogs and cats. One recurring theme during the discussions was our paucity of scientific evidence about how to use antibiotics in certain situations. It’s really interesting when you compare antibiotic treatment regimens that are used in humans and standard practices for dogs and cats.… Continue Reading

Risk factors for MRSA in dogs

Posted in Dogs
A recent study just published in the journal Emerging Infectious Diseases evaluated risk factors for dogs having an infection with methicillin-resistant Staphylococcus aureus (MRSA) versus methicillin-susceptible S. aureus (MSSA). This study, headed by Dr. Meredith Faires, compared dogs with MRSA versus MSSA infections from three different veterinary referral hospitals in Canada and the US. Among the more… Continue Reading

Antibiotic Awareness Day

Posted in Miscellaneous
European Antibiotic Awareness Day is an initiative of the European Centre for Disease Prevention and Control.  This year it falls on November 18.  The aim of the Day is to provide an annual opportunity for raising awareness about the threat to public health of antibiotic resistance and how to use antibiotics responsibly. Responsible use of… Continue Reading

Antibiotics, pets and Clostridium difficile

Posted in Clostridium difficile, Dogs
Clostridium difficile is a high-profile bacterium, being an important cause of illness and death in people. It can also be found in various animal species, including dogs and cats. In a study we published earlier this year (Lefebvre et al, Journal of the American Veterinary Medical Association, 2009), factors associated with acquisition of Clostridium difficile… Continue Reading

How not to use antibiotics

Posted in Dogs
A reader’s question to InsideToronto.com highlights numerous issues with antibiotic misuse is pets (and people). Here’s the situation, with my comments. The reader has a cocker spaniel that’s had a urinary tract infection for a year. She took it to her vet and a urine culture was recommended but she declined it. Antibiotics were prescribed… Continue Reading