Worms & Germs Blog

Tag Archives: antibiotics

Antimicrobial use surveillance: Canada

Posted in Animals
The 2017 Canadian Antimicrobial Resistance Surveillance System (CARSS) report was just released, and as always it contains a lot of data (up to and including 2016). Some are interesting, some are concerning, some are encouraging. I’m not going to try to distill a 90 page report into a quick blog post, so I’ll cover a… Continue Reading

WHO Guidelines on Use of Medically Important Antimicrobials in Food-Producing Animals

Posted in Other animals, Other diseases
The World Health Organization has released new guidelines on the use of “medically important antimicrobials” (MIAs) in food animals. Here’s a list of their recommendations, along with the strength of each recommendation and quality of evidence behind it. We recommend an overall reduction in use of all classes of medically important antimicrobials in food-producing animals (Strong… Continue Reading

Antibiotics and dairy calves

Posted in Other animals, Other diseases
From CANresist.blog: Reducing Antibiotic Use in Dairy Calves This topic’s huge, and there’s always a risk of trying to oversimplify the problem or solutions. However, some solutions for some issues might be fairly straightforward. Whether it’s on a farm, in a hospital or in a doctors office, there are situations where I think it’s widely… Continue Reading

CANresist

Posted in Birds, Cats, Dogs, Horses, Other animals
Introducing CANresist, a new initiative aimed at fostering antibiotic stewardship in Canada across the human and animal health fields and beyond, in order to maintain the effectiveness of these life-saving drugs. Follow us at CANresist.com or CANresist.blog, or on Facebook. Also check out our Twitter feed @CANADAresist, including our #mylastantibiotic tag to talk about the last time… Continue Reading

Colistin Resistance in Pets

Posted in Cats, Dogs
I’ve had a lot of emails over the past few months from colleagues from other countries, asking if we’re finding much mcr-1 in Canada. mcr-1 is a gene that makes bacteria resistant to colistin, a “drug of last resort” in people with some highly resistant infections.  The gene has emerged in bacteria from both animals… Continue Reading

Not all bugs must die…subclinical bacteriuria in cats

Posted in Cats
Since we developed the first version of the ISCAID guidelines for diagnosis and management of urinary tract infections in dogs and cats in 2011 (revision currently underway), most discussion about them has probably revolved around our recommendations for animals with subclinical bacteriuria. In this condition, an animal has bacteria in the urine, but no signs of disease.… Continue Reading

Pre-multidrug-resistant TB in a dog

Posted in Dogs, Other diseases
A few times a year I get questions about tuberculosis (TB) in dogs, typically after a person is diagnosed with active TB and people want to know what the risks are to, and from, their dog. It’s often tough to answer those questions, because there’s limited information available. Risks exist, but how much of a… Continue Reading

Move Over mcr-1. You’re Old News.

Posted in Other animals, Other diseases
Recent identification of mcr-1, a gene that makes bacteria resistant to colistin (an antibiotic of last resort) raised a lot of concern. Now, there’s another one to be worried about, as a related gene, mcr-2 has been identified (Xavier et al, Eurosurveillance, July 2016). In this study, 105 colistin-resistant E. coli from calves and piglets… Continue Reading

New superbug in dogs and cats: mcr-1

Posted in Cats, Dogs
A few years ago, the New Delhi metallobetalactamase-1 (NDM-1) antibiotic resistance gene attracted a lot of attention. This resistance gene can be found in (and passed between) a variety of bacteria, and bacteria possessing this gene are resistant to a wide range of drugs. A drug of last resort for those infections is colistin (a… Continue Reading

Get Smart About Antibiotics Week

Posted in Cats, Dogs, Horses, Miscellaneous, Other animals
Since their discovery in the mid-1900s (which really wasn’t that long ago in the grand scheme of things), antibiotics have revolutionized human medicine, veterinary medicine and even food production.  They save lives and prevent illness, helping to make both people and animals healthier, happier and more efficient at what they do.  But if we want… Continue Reading

White House antibiotic resistance action plan

Posted in Other diseases
The White House has released a "National Action Plan for Combating Antibiotic Resistant Bacteria". This follows on the heels of "Executive Order 13676: Combating Antibiotic-Resistant Bacteria" which was issued by President Barack Obama on September 18, 2014, along with the "National Strategy for Combating Antibiotic-Resistant Bacteria" presented by the President’s Council of Advisors on Science… Continue Reading

Antibiotics in animals: ACVIM consensus statement

Posted in Cats
Every year, the American College of Veterinary Internal Medicine (ACVIM) commissions "consensus statements" on specific topics. They’re developed by an expert panel, put up for review by ACVIM members (board certified veterinary internal medicine specialists), and published in the Journal of Veterinary Internal Medicine. Hot off the (electronic) press is the 2015 ACVIM Consensus Statement… Continue Reading

Canadian human antimicrobial use report, 2012/2013

Posted in Miscellaneous
The Public Health Agency of Canada (PHAC) has released the 2012/2013 Human Antimicrobial Drug Use Report. Why write about this on a site dedicated to zoonotic diseases and diseases of animals? For a few different reasons, actually. One is that we have to realize that antibiotics (and bacteria) don’t care if drugs are used on… Continue Reading

More bad news on the MRSP front

Posted in Dogs
Well, "news" perhaps isn’t the best description since we’ve been seeing it for a while, but a paper in an upcoming edition of the Journal of Clinical Microbiology (Gold et al. 2014) entitled "Amikacin resistance in Staphylococcus pseudintermedius isolated from dogs" provides published support for the trend we’ve been seeing. Staphylococcus pseudintermedius is an important… Continue Reading

Cry me a river…crackdown on Angels’ Eyes

Posted in Dogs
Finally. While having nothing to do with my previous rants on the topic, the FDA has issued warning letters to the manufacturers of Angels’ Eyes and similar products that are vaguely disguised antibiotics sold for purely cosmetic reasons, and without a veterinary prescription. These products have been widely available to decrease tear staining (hardly a… Continue Reading

FDA releases 2011 antimicrobial resistance data

Posted in Other animals
The US Food and Drug Administration has released the 2011 NARMS (National Antimicrobial Resistances Monitoring System) executive report. It’s a good-news/bad-news outcome, which may be as good as can be expected, but at least there’s some good news. Here are some areas that were highlighted by the FDA. Eighty-five percent of non-typhoidal Salmonella collected from humans… Continue Reading

Guidelines for the diagnosis and treatment of pyoderma in dogs

Posted in Dogs
Clinical guidelines are fairly new (and limited) in veterinary medicine, although they’re widespread in human medicine. Following up on recent guidelines for diagnosis of treatment of urinary tract infections in dogs and cats, a working group from the International Society for Companion Animal Infectious Diseases (ISCAID) has completed guidelines for the treatment of a common… Continue Reading

“Angels’ eyes”…and this is a good idea because…?

Posted in Cats
Antibiotic resistance is a big deal. Lots of people and animals die because of it every year. It costs the healthcare systems (human and veterinary) tremendous amounts of money and it’s not getting better. It’s been clear for years that we have to do a better job of using antibiotics responsibly, in both animals and… Continue Reading

The “criticall important antibiotic” debate

Posted in Other diseases
Last week, I mentioned the antibiotic use plenary session at the ASM-ESCMID conference on methicillin-resistant staphylococci in animals. The session was designed to discuss the use of "critically important antibiotics" in companion animals – drugs like carbapenems (imipenem, meropenem) and vancomycin, which are used for treating serious multidrug-resistant infections in people as well. After the… Continue Reading

The big gun antibiotic controversy

Posted in Dogs
I’m getting ready for next week’s ASM/ESCMID conference on methicillin-resistant staphylococci in animals, for which I’m involved in a plenary session about critically important antibiotics in companion animals. The whole area of antibiotics and animals in complex and controversial (and made worse by political agendas, lack of evidence and confusion about different issues). Anyway, one… Continue Reading